After completing the school of applied arts in Sarajevo, Ivica Šiško graduated from the Academy of Fine Arts in Zagreb in the class of Frano Baća in 1974, after which he was an associate of the Master Workshop of Krsto Hegedušić and Ljubo Ivančić from 1974-1978.

In the drawings and graphics created around 1975, he uses an expressive line to analyse movement in space filled with organic forms and figurative details. With his peculiar imagination and phantasmagorical vision, he is one of the protagonists of postmodernist painting in the 80s in Croatia.

With ornamental transformations of animal and plant motifs, he approaches the new Art Nouveau, while in mythological scenes he recalls Botticelli, Cranach, El Greco. Sophisticated graphics, dynamically understood forms and color symbolism are the main carriers of the energy of that painting in which natural processes and the vital force of existence are sublimated.

His significant artistic work on small buildings was also noted, such that he designed the look of the Memorial Center in Rujani and decorated the church of St. George the Martyr, within which the Memorial Center is located. He made for the church of St. Anthony of Padua in Čakovec, a number of mosaics depicting: Ascension of Jesus; Virgin Mary, St. Anne and St. Joachim; St. Leopold Mandić; Baptism of Jesus; Jesus and children and multiplication of bread.